
A major advance technological innovation
The ZAP-X: a high-precision X-ray scalpel
Lariboisière AP-HP Hospital and ELSAN are joining forces to offer patients state-of-the-art radiosurgery equipment: ZAP-X.
Zap-X at Lariboisière Hospital AP-HP Paris
The Lariboisière AP-HP hospital is home to ZAP-X in a listed building in the hospital's west wing, covering an area of 100m2.




Equipment with multiple benefits for patients
Less side effects
Optimization of treatment planning
Fast processing
Comfort
From CyberKnife® to Zap-X
Invented by Professor John Adler, who had already developed the Cyberknife® machine, the ZAP-X uses high-energy X-rays to create 360° beams within the lesion or tumor thanks to its gyroscopic design. It performs precise
3D tracking of the patient’s position using an onboard control imaging system that produces images every
45 seconds. In addition, it features the first real-time monitoring system for the administration of treatment to the patient, reducing the risk of human and mechanical errors with an automatic shutdown in the event of a discrepancy between the planned dosimetry and that during treatment.
Greater precision
ZAP-X works on the principle of intersecting mini-X-ray beams produced by a miniaturized particle gas pedal, enabling it to target any intracranial lesion or lesion of the cervical spinal cord. The machine’s technical design enables very high doses to be delivered with great precision, while minimizing the risk of damage to surrounding healthy tissue (notably by reducing the radiation scattered around the target). Compared with other irradiation methods, ZAP-X stands out for its ability to deliver rapid treatment, and to treat tumors or other lesions that are difficult to access or difficult to operate on, with acceptable risks.


Vermeer and the art of precision

An unprecedented collaboration
Adaptability to different
types of injuries
Functional disorders (certain types of trigeminal neuralgia and facial vascular pain, certain specific forms of epilepsy, or certain types of abnormal movements).
Benign intracranial tumors (mainly meningiomas and schwannomas) or malignant tumors (mainly brain metastases, but also chordomas of the skull base);
Cerebral vascular anomalies (mainly cerebral arteriovenous malformations and cavernomas);
Benefits of Zap-X technology
As it is a non-invasive technology, ZAP-X can avoid surgery in a number of cases, which can be a major advantage for patients who are not candidates for surgery due to the location of the tumor or their general condition.
Radiosurgery may also be offered as a complement to surgery when a fragment of the tumor or lesion has been deliberately left in place due to the neurological risk of surgery.
Overall, as a complement or alternative to surgery, ZAP-X radiosurgery greatly reduces risks.
Thanks to its ability to deliver highly localized and well-targeted doses, ZAP-X can treat tumors located in complex or hard-to-reach anatomical areas, which is not always possible with other radiotherapy methods. This is particularly important for certain areas of vision and hearing that are particularly sensitive to radiation.



